Indole → HCID 68109573, compound

Participants

Reaction Steps

The product of step B and indole were reacted using the procedure of Example 41, step C to provide tert-butyl 8-(1H-indol-1-ylsulfonyl)-6-chloro-3,4-dihydrobenzofuro[3,2-c]pyridine-2(1H)-carboxylate (35 mg, 45%) as an off-white solid: 1H NMR (CDCl3, 300 MHz) δ 8.00 (d, J=8.1 Hz, 1H), 7.89 (s, 1H), 7.73 (d, J=1.5 Hz, 1H), 7.58 (d, J=3.6 Hz, 1H), 7.52 (d, J=7.8 Hz, 1H), 7.36-7.30 (m, 1H), 7.25-7.20 (m, 1H), 6.69-6.68 (m, 1H), 4.52 (s, 2H), 3.80 (t, J=5.4 Hz, 2H), 2.88 (t, J=5.1 Hz, 2H), 1.50 (s, 9H).

Provenance & Evidence