Benzenesulfinic acid, sodium salt → HCID 68109925, compound

Participants

Reaction Steps

The product of step B was coupled with sodium benzenesulfinate using the procedure of Example 29, step C. Purification by flash column chromatography (SiO2, 7:3 hexane/ethyl acetate) provided tert-butyl 6-fluoro-8-phenylsulfonyl-3,4-dihydrobenzofuro[3,2-c]pyridine-2(1H)-carboxylate (141 mg, 57%) as a light-yellow solid: 1H NMR (CDCl3, 300 MHz) δ 7.97-7.94 (m, 2H), 7.88 (br s, 1H), 7.61-7.47 (m, 4H), 4.57 (s, 2H), 3.84 (t, J=5.4 Hz, 2H), 2.89 (br s, 2H), 1.51 (s, 9H).

Provenance & Evidence