Benzenesulfinic acid, sodium salt → HCID 68108906, compound

Participants

Reaction Steps

The product of step E was coupled with sodium benzenesulfinate following the procedure of Example 29, step C. Purification by flash column chromatography (SiO2, 70:30 hexanes/ethyl acetate) provided tert-butyl 8-(phenylsulfonyl)-4,5-dihydro-1H-benzofuro[3,2-c]azepine-2(3H)-carboxylate (106 mg, 34%) as a pale yellow solid: 1H NMR (CDCl3, 300 MHz) δ 8.04-7.87 (m, 3H), 7.83-7.72 (m, 1H), 7.60-7.41 (m, 4H), 4.64-4.61 (m, 2H), 3.67 (br s, 2H), 3.03 (t, J=6.3 Hz, 2H), 1.99 (br s, 2H), 1.53-1.25 (m, 9H).

Provenance & Evidence