Benzenesulfinic acid, sodium salt → HCID 68109053, compound

Participants

Reaction Steps

The product of step E was coupled with sodium benzenesulfinate following the procedure of Example 29, step C. Purification by flash column chromatography (SiO2, 70:30 hexanes/ethyl acetate) provided tert-butyl 9-(phenylsulfonyl)-4,5-dihydro-1H-benzofuro[3,2-c]azepine-2(3H)-carboxylate (22 mg, 22%) as a light yellow solid: 1H NMR (CDCl3, 300 MHz) δ 8.09 (br s, 1H), 8.00-7.91 (m, 2H), 7.86-7.77 (m, 1H), 7.58-7.37 (m, 4H), 4.68-4.38 (m, 2H), 3.70 (br s, 2H), 3.01 (t, J=6.0 Hz, 2H), 2.09-1.92 (m, 2H), 1.53-1.20 (m, 9H).

Provenance & Evidence