Phenol → HCID 68109648, compound

Participants

Reaction Steps

The product of step A was converted to the phenol derivative using the procedure of Example 54, step A. Purification by flash column chromatography (SiO2, 3:7 hexane/ethyl acetate) provided tert-butyl 8-((1H-indol-5-yl)sulfonyl)-6-hydroxy-3,4-dihydrobenzofuro[3,2-c]pyridine-2(1H)-carboxylate (90 mg, 65%) as a yellow solid: 1H NMR (CDCl3, 400 MHz) δ 8.98 (s, 1H), 8.22 (s, 1H), 7.77-7.17 (m, 4H), 6.51 (s, 1H), 4.49 (s, 2H), 3.80-3.67 (m, 2H), 2.80-2.63 (m, 2H), 1.49 (s, 9H).

Provenance & Evidence