Benzenesulfinic acid, sodium salt → HCID 68108935, compound

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Reaction Steps

The product of step E and sodium benzenesulfinate were coupled using the procedure of Example 29, step C. Purification by flash column chromatography (SiO2, 1:1 hexane/ethyl acetate) provided tert-butyl 6-(hydroxymethyl)-8-(phenylsulfonyl)-3,4-dihydrobenzofuro[3,2-c]pyridine-2(1H)-carboxylate (33 mg, 44%) as a colorless oil: 1H NMR (CDCl3, 400 MHz) δ 8.03 (s, 1H), 7.99-7.93 (m, 2H), 7.88 (d, J=1.6 Hz, 1H), 7.58-7.46 (m, 3H), 4.99 (d, J=6.0 Hz, 2H), 4.56 (s, 2H), 3.82 (s, 2H), 2.87 (s, 2H), 2.13 (t, J=6.0 Hz, 1H), 1.51 (s, 9H).

Provenance & Evidence