Benzenesulfinic acid, sodium salt → HCID 68108892, compound

Participants

Reaction Steps

The product of step B and sodium benzenesulfinate were coupled using the procedure of Example 29, step C. Purification by flash chromatography (SiO2, 80:20 hexanes/ethyl acetate) provided tert-butyl 6-((1H-pyrazol-1-yl)methyl)-8-(phenylsulfonyl)-3,4-dihydrobenzofuro[3,2-c]pyridine-2(1H)-carboxylate (18 mg, 39%) as a yellow solid: 1H NMR (CDCl3, 300 MHz) δ 8.05-7.96 (m, 1H), 7.95-7.85 (m, 2H), 7.62-7.40 (m, 6H), 6.32-6.25 (m, 1H), 5.60 (s, 2H), 4.56 (s, 2H), 3.83 (t, J=5.1 Hz, 2H), 2.95-2.80 (m, 2H), 1.51 (s, 9H).

Provenance & Evidence