Benzenesulfinic acid, sodium salt → HCID 68109753, compound

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Reaction Steps

The product of step A and sodium benzenesulfinate were coupled using the procedure of Example 29, step C. Purification by flash column chromatography (SiO2, 1:4 dichloromethane/ethyl acetate) provided tert-butyl 6-(methylcarbamoyl)-8-(phenylsulfonyl)-3,4-dihydrobenzofuro[3,2-c]pyridine-2(1H)-carboxylate (41 mg, 68%) as a yellow oil: 1H NMR (CDCl3, 400 MHz) δ 8.54 (d, J=2.0 Hz, 1H), 8.18 (s, 1H), 7.97 (d, J=7.2 Hz, 2H), 7.59-7.44 (m, 3H), 7.28 (s, 1H), 4.59 (s, 2H), 3.87 (t, J=5.2 Hz, 2H), 3.10 (d, J=4.8 Hz, 3H), 3.00-2.88 (m, 2H), 1.51 (s, 9H).

Provenance & Evidence