Morpholine → 7-Morpholinylheptylphthalimide

HRID 21795Notes

Reaction equation

HRID 21795 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]1[CH:19]=[CH:18][CH:17]=[C:11]2[C:12]([NH:14][C:15](=[O:16])[C:10]=12)=[O:13].[NH:20]1[CH2:25][CH2:24][O:23][CH2:22][CH2:21]1>C(#N)C>[N:20]1([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]2[CH:19]=[CH:18][CH:17]=[C:11]3[C:12]([NH:14][C:15](=[O:16])[C:10]=23)=[O:13])[CH2:25][CH2:24][O:23][CH2:22][CH2:21]1

Participants

4

Reactant 2

HCID 8083MorpholineHCID 199334987-Bromoheptylphthalimide

Product 1

HCID 536569877-Morpholinylheptylphthalimide

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

7-Bromoheptylphthalimide (489 mg; 2.0 mmoles) and morpholine (0.35 ml; 4.0 mmoles) were dissolved in anhydrous acetonitrile (5 ml). Reaction times and process as per Example 1.

Workup

  1. customReaction times and process as per Example 1

Sources & evidence

ORD record
ord-4d0ad2a133964c5cb92778bcdf764af7
Source dataset
uspto-grants-1995_06
Patent number
US05424451

Reaction notes

Loading…