反应详情

414 g (3 mol) of the ethyl(2-hydroxyethyl)phosphinic acid obtained (produced as in Example 8) are at 85° C. dissolved in 400 ml of toluene and admixed with 888 g (12 mol) of butanol. At a reaction temperature of about 100° C., the water formed is removed by azeotropic distillation to leave 500 g (86% of theory) of butyl ethyl(2-hydroxyethyl)phosphinate purified by distillation at reduced pressure.

1. custom(produced as in Example 8)
2. customare at 85° C.
3. customis removed by azeotropic distillation