N-methyl-2-pyrrolidone → HCID 86701347, compound

Participants

Reaction Conditions

Reaction Steps

Under the nitrogen atmosphere, 9-(7-methoxynaphthalen-2-yl)-10-(naphthalen-1-yl)anthracene (17.5) as the third intermediate compound, pyridine hydrochloride (22.0 g) and N-methylpyrrolidone (35 ml) were added to a flask and stirred for 6.5 hours at 200° C. Once the heating is completed, the reaction solution was cooled to 100° C. or less, added with water, and the precipitated solid was collected by suction filtration. The crude product obtained was purified by silica gel column chromatography (solvent: toluene) to give 7-(10-(naphthalen-1-yl)anthracen-9-yl)naphthalene-2-ol (16.0 g) as a fourth intermediate compound. The scheme is shown in the following “Reaction 5”.

Provenance & Evidence