Hydrazine → 8-Morpholinooctylamine

HRID 21799Notes

Reaction equation

HRID 21799 reaction equation
[NH2:1]N.[N:3]1([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]C2C=CC=C3C(NC(=O)C=23)=O)[CH2:8][CH2:7][O:6][CH2:5][CH2:4]1>CO>[N:3]1([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][NH2:1])[CH2:4][CH2:5][O:6][CH2:7][CH2:8]1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 537680558-Morpholinyloctylphthalimide

Product 1

HCID 222376608-Morpholinooctylamine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Hydrazine (aqueous solution at 35% by wt.) (0.15 ml; 1.6 mmoles) was added to 8-morpholinyloctylphthalimide (275 mg; 0.8 mmoles) in methanol (5 ml) and the resulting solution was refluxed. Reaction times and process as per Example 1.

Workup

  1. temperaturethe resulting solution was refluxed
  2. customReaction times and process as per Example 1

Sources & evidence

ORD record
ord-6e7e1bb58d654f78818c1c604ca73fed
Source dataset
uspto-grants-1995_06
Patent number
US05424451

Reaction notes

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