HCID 22489889, compound → HCID 69799249, compound

HRID 2179988Notes

Reaction equation

HRID 2179988 reaction equation
[Cl:1][CH2:2][CH2:3][C@@H:4]([C:6]1[CH:10]=[CH:9][O:8][N:7]=1)[OH:5].[F:11][C:12]1[C:13]([CH3:21])=[CH:14][C:15](O)=[C:16]([CH:19]=1)[C:17]#[N:18]>>[Cl:1][CH2:2][CH2:3][C@@H:4]([O:5][C:15]1[CH:14]=[C:13]([CH3:21])[C:12]([F:11])=[CH:19][C:16]=1[C:17]#[N:18])[C:6]1[CH:10]=[CH:9][O:8][N:7]=1

Participants

3

Reactant 2

HCID 22489889HCID 22489889, compoundHCID 69799074HCID 69799074, compound

Product 1

HCID 69799249HCID 69799249, compound

Procedure

The product of step (d) (0.47 g) was reacted with 5-fluoro-2-hydroxy-4-methylbenzonitrile using the procedure described for Example 5(a) to afford the product as a white solid (0.4 g).

Sources & evidence

ORD record
ord-eb32f1fe375e4db79f4b77f6083b5c54
Source dataset
uspto-grants-2005_05
Patent number
US06887871B2

Reaction notes

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