Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cyclohexane | HCID 8078 | — |
| Reactant | 1-Benzyl-4-methanesulfonyl-piperazine | HCID 779507 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(Methylsulfonyl)piperazine | HCID 709161 | 98.2% |
Reaction Steps
A suspension of 1-benzyl-4-methylsulfonylpiperazine (2.5 g, 9.8 mmol) and cyclohexane (30 ml) in ethanol (70 ml) containing 20% palladium hydroxide on carbon (500 mg) was stirred at 80° C. for 4 hours. The mixture was cooled, filtered and the filtrate was evaporated to give 1-methylsulfonylpiperazine (1.58 g, 98%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06887874B2 |
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| Source dataset | uspto-grants-2005_05 |
|---|
| ORD ID | ord-da0cb74559c940c19fe510a6d1b84d00 |
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| Source note | uspto-grants-2005_05 |
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