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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2180152Generated: October 31, 2026

4-Pyridineethanol → HCID 22490037, compound

https://huagongshe.com/reaction/2180152

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PyridineethanolHCID 72921—
Reactant4-(4-Fluoro-2-methylindol-5-yloxy)-7-hydroxy-6-methoxycinnolineHCID 135749776—
ProductHCID 22490037HCID 2249003757%

Reaction Steps

Using an analogous procedure to that described in Example 20, 4-(4-fluoro-2-methylindol-5-yloxy)-7-hydroxy-6-methoxycinnoline (0.2 g, 0.6 mmol), (prepared as described in Example 4), was reacted with 4-(2-hydroxyethyl)pyridine (0.11 g, 0.9 mmol), (Zhur. Obshchei. Khim. 1958, 28, 103-110), to give 4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxy-7-(2-(4-pyridyl)ethoxy)cinnoline (0.15 g, 57%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06887874B2
Source datasetuspto-grants-2005_05
ORD IDord-2e9e04bd61194efeb1b86a9620b9cc76
Source noteuspto-grants-2005_05