HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Pyridineethanol → HCID 22490037, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Pyridineethanol | HCID 72921 | — |
| Reactant | 4-(4-Fluoro-2-methylindol-5-yloxy)-7-hydroxy-6-methoxycinnoline | HCID 135749776 | — |
| Product | HCID 22490037 | HCID 22490037 | 57% |
Reaction Steps
Using an analogous procedure to that described in Example 20, 4-(4-fluoro-2-methylindol-5-yloxy)-7-hydroxy-6-methoxycinnoline (0.2 g, 0.6 mmol), (prepared as described in Example 4), was reacted with 4-(2-hydroxyethyl)pyridine (0.11 g, 0.9 mmol), (Zhur. Obshchei. Khim. 1958, 28, 103-110), to give 4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxy-7-(2-(4-pyridyl)ethoxy)cinnoline (0.15 g, 57%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06887874B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-2e9e04bd61194efeb1b86a9620b9cc76 |
| Source note | uspto-grants-2005_05 |