反应详情

A solution of Example 1C (1.10 g, 3.65 mmol) in dichloromethane at 0° C. was treated with dicyclohexylcarbodiimide (0.83 g, 4.02 mmol), stirred for 30 minutes, treated with benzyl carbazate (0.69 g, 4.02 mmol), warmed to room temperature, and stirred for 32 hours. The mixture was filtered, and concentrated, and the concentrate was purified by flash column chromatography on silica gel with ethyl acetate in hexanes to provide the desired product.

1. stirringstirred for 32 hours
2. filtrationThe mixture was filtered
3. concentrationconcentrated
4. customthe concentrate was purified by flash column chromatography on silica gel with ethyl acetate in hexanes