HCID 69797268, compound → HCID 91543769, compound

HRID 2180229Notes

Reaction equation

HRID 2180229 reaction equation
[C:1]([O:5][C:6]([NH:8][C@H:9]([CH2:26][CH:27]1[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]1)[CH:10]([OH:25])[C:11]([NH:13][NH:14]C(OCC1C=CC=CC=1)=O)=[O:12])=[O:7])([CH3:4])([CH3:3])[CH3:2]>CO.[Pd].[C]>[CH:27]1([CH2:26][C@@H:9]([NH:8][C:6](=[O:7])[O:5][C:1]([CH3:3])([CH3:2])[CH3:4])[CH:10]([OH:25])[C:11]([NH:13][NH2:14])=[O:12])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]1

Participants

4

Reactant 1

HCID 69797268HCID 69797268, compound

Product 1

HCID 91543769HCID 91543769, compound

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 887MethanolSolvent

Procedure

A solution of Example 13A (0.37 g, 0.82 mmol) in methanol (15mL) was treated with Pd-carbon (0.05 g), stirred under a hydrogen atmosphere for 16 hours, filtered, and concentrated to provide the desired product.

Workup

  1. filtrationfiltered
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-51a2d4a5aad94c9d95d244a4a8c5c9de
Source dataset
uspto-grants-2005_05
Patent number
US06887863B2

Reaction notes

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