Methanesulfonyl chloride → HCID 9978516, compound

Participants

Reaction Steps

Using the general method of Example 245, 1-(4-aminobutyl)-2-pentyl-1H-imidazo[4,5-c]quinolin-4-amine (1.50 g, 4.6 mmol) was reacted with methanesulfonyl chloride (0.57 mL, 7.4 mmol) to provide 636 mg of N-[4-(4-amino-2-pentyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamide as an off white solid, m.p. 136.8-138.1° C. Analysis: Calculated for C20H29N5O2S: % C, 59.53; % H, 7.24; % N, 17.35; Found: % C, 59.50; % H, 7.31; % N, 16.80.

Provenance & Evidence