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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2180309Generated: October 30, 2026

Benzoic Acid → Benzimidazole

https://huagongshe.com/reaction/2180309

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoic AcidHCID 243—
ReactantO-PhenylenediamineHCID 7243—
ProductBenzimidazoleHCID 5798—

Reaction Steps

A known method consists in condensing 1,2-diaminobenzene with benzoic acid in the presence of polyphosphoric acid to give benzimidazole, and sulphonating this with, for example, chlorosulphonic acid (Am. Chem. Soc. 79, 427 (1957)).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06888005B2
Source datasetuspto-grants-2005_05
ORD IDord-45aacb5126ec4483bc14bcc52b4d6cb0
Source noteuspto-grants-2005_05