Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | HCID 67019637 | HCID 67019637 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | HCID 73708685 | HCID 73708685 | 101.1% |
Reaction Steps
To a suspension of 3-[3-(2-methoxy-phenylsulfamoyl)-phenyl]-acrylic acid (15c) (0.36 g, 1.04 mmol) in dichloromethane (4 ml) oxalyl chloride (0.27 ml, 3.12 mmol) and one drop of dimethylformamide were added. The reaction mixture was stirred at 40° C. for one hour and concentrated under reduced pressure to give crude title compound (0.37 g, 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06888027B2 |
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| Source dataset | uspto-grants-2005_05 |
|---|
| ORD ID | ord-586cf3d21b5149caae756804238d0fa5 |
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| Source note | uspto-grants-2005_05 |
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