Sodium Hydroxide → HCID 60003031, compound

Participants

Reaction Steps

Following General Procedure G, ethyl 7-(4-isopropyl-7-methoxy-2,2-dimethyl-2H-chromen-6-yl)-3-methyl-octa-2E,4E,6Z-trienoate (Compound 33, 60 mg, 0.15 mmol) was hydrolyzed with 1 M NaOH. Purification by column chromatography (silica gel, 30% ethyl acetate in hexanes) followed by recrystallization from acetonitrile yielded the title compound as a yellow solid.

Provenance & Evidence