Sodium Hydroxide → HCID 60003044, compound

Participants

Reaction Steps

Following General Procedure G, ethyl 7-(7-ethoxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl)-3-methyl-octa-2E,4E,6Z-trienoate (Compound 37, 55 mg, 0.13 mmol) was hydrolyzed with 1M NaOH to yield the title compound as a yellow solid after purification by column chromatography (silica gel, 30% ethyl acetate in hexanes) followed by recrystallization from acetonitrile to yield the title compound as a light yellow solid.

Provenance & Evidence