Sodium Hydroxide → HCID 60003029, compound

Participants

Reaction Steps

Following General Procedure G, ethyl 7-(8-chloro-4-isopropyl-7-methoxy-2,2-dimethyl-2H-chromen-6-yl)-3-methyl-octa-2E,4E,6Z-trienoate (Compound 39, 53 mg, 0.12 mmol) was hydrolyzed with 1M NaOH. Purification by column chromatography (silica gel, 20% to 30% ethyl acetate in hexanes) followed by recrystallization from acetonitrile gave rise to the title compound as a light yellow solid.

Provenance & Evidence