HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → 1-(4-Isopropyl-7-ethoxy-2,2-dimethyl-2H-chromen-6-yl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 7-Hydroxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl-ethanone | HCID 22490917 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-(4-Isopropyl-7-ethoxy-2,2-dimethyl-2H-chromen-6-yl)ethanone | HCID 22491047 | — |
Reaction Steps
As described in General Procedure A, a solution of 1-(7-hydroxy-4 isopropyl-2,2-dimethyl-2H-chromen-6-yl)-ethanone (Compound 62, 205 mg, 0.69 mmol) in acetone were added ethyl iodide (0.3 mL, 3.45 mmol) and potassium carbonate (476 mg, 3.45 mmol) to give rise to the title compound as a colorless oil after purification by flash chromatography (silica gel, 5% ethyl acetate in hexanes).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06887896B1 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-14b050941e6a48f2a88d3abc76f81f9e |
| Source note | uspto-grants-2005_05 |