Diisobutylaluminumhydride → HCID 86759707, compound

Participants

Reaction Steps

Following General Procedure L, ethyl (2E)-3-(7-ethoxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl)-2-fluoro-but-2-enoate (Compound 72, 163,mg, 0.44 mmol) and diisobutylaluminum hydride (1M in hexanes, 1.74 mL, 1.74 mmol) were reacted to give the title compound as a colorless oil after purification by flash chromatography (silica gel, 1:9 to 1:4 ethyl acetate/hexane).

Provenance & Evidence