反应详情

Following General Procedure L, ethyl (2E)-3-(7-butoxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl)-2-fluoro-but-2-enoate (Compound 74, 133 mg, 0.34 mmol) and diisobutylaluminum hydride (1 M in hexanes, 1.37 mL, 1.37 mmol) were reacted to give the title compound as a colorless oil after purification by flash chromatography (silica gel, 1:9 ethyl acetate/hexane).

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