Diisobutylaluminumhydride → HCID 22490895, compound

Participants

Reaction Steps

Following General Procedure L, ethyl (2E)-3-(7-ethoxy-2,2-dimethyl-4-phenyl-2H-chromen-6-yl)-2-fluoro-but-2-enoate (Compound 75, 160 mg, 0.38 mmol) and diisobutylaluminum hydride (1 M in hexanes, 1.51 mL, 1.51 mmol) were reacted to give the title compound as a colorless oil after purification by flash chromatography (silica gel, 1:4 ethyl acetate/hexane).

Provenance & Evidence