Diisobutylaluminumhydride → HCID 69731287, compound

Participants

Reaction Steps

Following General Procedure L, ethyl 2-fluoro-3-(7-methoxy-2,2,4-trimethyl-2H-chromen-6-yl)-pent-2-enoate (Compound 77, 195 mg, 0.56 mmol) and a diisobutylaluminum hydride (1 M in hexanes, 1.68 mL, 1.68 mmol) were reacted to give the title compound as yellow solid after purification by flash chromatography (silica gel, 1:4 ethyl acetate/hexane).

Provenance & Evidence