HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisobutylaluminumhydride → HCID 69730120, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisobutylaluminumhydride | HCID 21225700 | — |
| Reactant | Ethyl (2E)-2-fluoro-3-(4-tert-butyl-7-methoxy-2,2-dimethyl-2H-chromen-6-yl)-pent-2-enoate | HCID 69732339 | — |
| Reactant | HCID 69732341 | HCID 69732341 | — |
| Product | HCID 69730120 | HCID 69730120 | — |
Reaction Steps
Following General Procedure L, ethyl 2-fluoro-3-(4-tert-butyl-7-methoxy-2,2-dimethyl-2H-chromen-6-yl)-pent-2-enoate (Compound 79, 90 mg, 0.23 mmol) and diisobutylaluminum hydride (1 M in dichloromethane, 0.7 mL, 0.7 mmol) were reacted to give the title compound as yellow solid after purification by flash chromatography (silica gel, 1:4 ethyl acetate/hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06887896B1 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-ac862349b5964b2a98c9e7c4f867c874 |
| Source note | uspto-grants-2005_05 |