HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → (2E,4E,6E)-7-(7-Butoxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl)-6-fluoro-3-methyl-octa-2,4,6-trienoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | ethyl (2E,4E,6E)-7-(7-butoxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl)-6-fluoro-3-methyl-octa-2,4,6-trienoate | HCID 86759710 | — |
| Product | (2E,4E,6E)-7-(7-Butoxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl)-6-fluoro-3-methyl-octa-2,4,6-trienoic acid | HCID 22490780 | — |
Reaction Steps
Following General Procedure G, a solution of ethyl (2E,4E,6E)-7-(7-butoxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl)-6-fluoro-3-methyl-octa-2,4,6-trienoate (Compound 113, 95 mg, 0.20 mmol) was hydrolyzed with NaOH to yield the title compound as a yellow solid after recrystallized from acetonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06887896B1 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-a0bce08afac04e92abdf46ab49d7c044 |
| Source note | uspto-grants-2005_05 |