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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2180541Generated: October 31, 2026

Triethyl 2-fluoro-2-phosphonoacetate → HCID 22490800, compound

https://huagongshe.com/reaction/2180541

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethyl 2-fluoro-2-phosphonoacetateHCID 2734865—
ReactantHCID 22490973HCID 22490973—
ProductHCID 22490800HCID 22490800—

Reaction Steps

Following General Procedure K, triethyl-2-fluoro-2-phosphonoacetate (1.8 mL, 8.64 nmol) and 1-(8-chloro-4-isopropyl-7-ethoxy-2,2-dimethyl-2H-chromen-6-yl)-ethanone (Compound 145, 930 mg, 2.88 mmol) were reacted to give the title compound as a colorless oil after purification by flash chromatography (silica gel, 1:9 ethyl acetate/hexane).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06887896B1
Source datasetuspto-grants-2005_05
ORD IDord-8b4ebeb93bda44d59d13120c0df00c1c
Source noteuspto-grants-2005_05