Tetrapropylammonium → HCID 22490981, compound

Participants

Reaction Steps

Following General Procedure M, 3-(8-chloro-7-isopropoxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl)-2-fluoro-but-2-en-1-ol (Compound 156,0.74 g, 1.9 mmol), tetrapropylammonium perrunthenate (TPAP, 0.034 g, 0.101 mmol), and 4-methylmorpholine N-oxide (NMO, 0.34 g, 2.9 mmol) were reacted to give the title compound as a pale yellow solid after purification by flash chromatography (silica gel column, 20% ethyl acetate in hexanes).

Provenance & Evidence