Tetrapropylammonium → HCID 86597837, compound

Participants

Reaction Steps

Following General Procedure M, 3-(8-chloro-7-isopropoxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl)-2-fluoro-pent-2-en-1-ol (Compound 157, 0.90 g, 2.26 mmol), tetrapropylammonium perrunthenate (TPAP, 0.04 g, 0.11 mmol), and 4-methylmorpholine N-oxide (NMO, 0.40 g, 3.4 mmol) were reacted to give the title compound as a pale yellow solid after purification by flash chromatography (silica gel, 10% ethyl acetate in hexanes).

Provenance & Evidence