Diisobutylaluminumhydride → HCID 69731067, compound

Participants

Reaction Steps

Following General Procedure G-1, ethyl (2E)-3-(3-ethoxy-5,5-dimethyl-5,6-dihydro-naphthalen-2-yl)-2-fluoro-pent-2-enoate (Compound A-41, 52 mg, 0.15 mmol) and diisobutylaluminum hydride (1M in methylene chloride, 0.36 mL, 0.36 mmol) were reacted to give the title compound as a colorless oil after purification by flash chromatography (silica gel, 10% ethyl acetate in hexanes).

Provenance & Evidence