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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2180579Generated: October 31, 2026

Dichloromethane → HCID 22490945, compound

https://huagongshe.com/reaction/2180579

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantMethyl morpholine oxideHCID 82029—
ReactantHCID 22491054HCID 22491054—
CatalystHCID 178419074HCID 178419074—
SolventAcetonitrileHCID 6342—
ProductHCID 22490945HCID 22490945—

Reaction Steps

As described in General Procedure H-1, (2E)-2-fluoro-3-(4,4-dimethyl-6-n-propoxy-1-isopropyl-3,4-dihydronaphthalen-7-yl)-2-butenol (Compound A-53, 0.024 g, 0.069 mmol), tetrapropylammonium perruthenate (0.012 g, 0.038 mmol) and 4-methylmorpholine N-oxide (0.022 g, 0.19 mmol) were reacted in acetonitrile (0.2 mL) and dichloromethane (1 mL) to produce the title compound as an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06887896B1
Source datasetuspto-grants-2005_05
ORD IDord-267e571b2f7040faa0d6dd9d1157466f
Source noteuspto-grants-2005_05