HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 86597846, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Tetrapropylammonium | HCID 9559 | — |
| Reactant | Methyl morpholine oxide | HCID 82029 | — |
| Reactant | HCID 69730999 | HCID 69730999 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Solvent | Hexane | HCID 8058 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86597846 | HCID 86597846 | — |
Reaction Steps
As described in General Procedure H-1, (2E)-3-(8-tert-butyl-3-ethoxy-5,5-dimethyl-5,6-dihydronaphthalen-2-yl)-2-fluoro-pent-2-en-1-ol (Compound A-56, 487 mg, 1.61 mmol), tetrapropylammonium peruthenate (316 mg, 2.7 mmol) and 4-methylmorpholine N-oxide (3.5 mg) were reacted in acetonitrile (4 mL) and dichloromethane (8 mL) to produce the title compound as an oil after flash chromatography (silica gel, 10% ethyl acetate in hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06887896B1 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-f9004df276cf4c5eb0db4fb65372dc69 |
| Source note | uspto-grants-2005_05 |