HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisobutylaluminumhydride → HCID 22490760, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisobutylaluminumhydride | HCID 21225700 | — |
| Reactant | ethyl (2E)-3-(4-bromo-3-ethoxy-8-isopropyl-5,5-dimethyl-5,6-dihydro-naphthalen-2-yl)-2-fluoro-but-2-enoate | HCID 86597852 | — |
| Product | HCID 22490760 | HCID 22490760 | — |
Reaction Steps
Following General Procedure G-1, ethyl (2E)-3-(4-bromo-3-ethoxy-8-isopropyl-5,5 dimethyl-5,6-dihydro-naphthalen-2-yl)-2-fluoro-but-2-enoate (Compound A-125, 1.2 g, 2.65 mmol) and diisobutylaluminum hydride (1 M in methylene chloride, 6.35 mL, 6.35 mmol) were reacted to give the title compound as a colorless oil after purification by flash chromatography (silica gel, 10% ethyl acetate in hexanes).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06887896B1 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-e57892dc8cf94bb89d96e96da7dde7bf |
| Source note | uspto-grants-2005_05 |