Diisobutylaluminumhydride → HCID 69731576, compound

Participants

Reaction Steps

Following General Procedure G-1, ethyl (2E)-3-(4-bromo-3-ethoxy-8-isopropyl-5,5-dimethyl-5,6-dihydro-naphthalen-2-yl)-2-fluoro-pent-2-enoate (Compound A-126, 1.07 g, 2.29 mmol) and diisobutylaluminum hydride (1M in methylene chloride, 5.5 mL, 5.5 mmol) were reacted to give the title compound as a colorless oil after purification by flash chromatography (silica gel, 10% ethyl acetate in hexanes).

Provenance & Evidence