Dichloromethane → HCID 22491001, compound

Participants

Reaction Steps

As described in General Procedure H-1, (2E>3-(4-bromo-3-ethoxy-8-isopropyl-5,5-dimethyl-5,6-dihydro-naphthalen-2-yl)- 2-fluoro-but-2-en-1-ol (Compound A-136, 908 mg, 2.2 mmol), tetrapropylammonium perruthenate (20 mg, 0.057 mmol) and 4-methylmorpholine N-oxide (516 mg, 4.4 mmol) were reacted in acetonitrile and dichloromethane to give the title compound after purification by flash column chromatography (silica gel, 5% ethyl acetate in hexane).

Provenance & Evidence