Methyl morpholine oxide → HCID 86597860, compound

Participants

Reaction Steps

As described in General Procedure H-1, (2E)-3-(4-chloro-3-ethoxy-8-isopropyl-5,5-dimethyl-5,6-dihydronaphthalen-2-yl)-2-fluoro-pent-2-en-1-ol (Compound A-145, 34 mg, 0.09 mmol) tetrapropylammonium perruthenate (10 mg, 0.028 mmol) and 4-methylmorpholine N-oxide (21 mg, 0.18 mmol) were reacted in dichloromethane to give the title compound after purification by flash column chromatography (silica gel, 10% ethyl acetate in hexanes).

Provenance & Evidence