Sodium Hydroxide → HCID 22490835, compound

Participants

Reaction Steps

As described in General Procedure J-1, ethyl (2E,4E,6E)-7-(4-bromo-3-isopropoxy-8-isopropyl-5,5-dimethyl-5,6-dihydro-naphthalen-2-yl)-6-fluoro-3-methyl-octa-2,4,6-trienoate (Compound A-161, 189 mg, 0.35 mmol) in ethanol was treated with a solution of 1 N NaOH to produce the title compound after purification by recrystallization from acetonitrile.

Provenance & Evidence