Sodium Hydroxide → HCID 22490846, compound

Participants

Reaction Steps

As described in General Procedure J-1, ethyl (2E,4E,6E)-7-(4-chloro-3-ethoxy 8-isopropyl-5,5-dimethyl-5,6-dihydronaphthalen-2-yl)-6-fluoro-3-methyl-octa-2,4,6-trienoate (Compound A-166, 0.14 g, 0.30 mmol) was hydrolyzed with 1 N NaOH to produce the title compound as a yellow solid after recrystallization from acetonitrile.

Provenance & Evidence