Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethylene Glycol | HCID 174 | — |
| Reactant | Thiophenol | HCID 7969 | — |
| Reactant | Dodecane | HCID 8182 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Iodo-3,5-dimethylbenzene | HCID 140924 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 11148597 | HCID 11148597 | — |
Reaction Steps
CuI (0.05 mmol) and potassium carbonate (276 mg, 2.0 mmol) were added to a screw-capped test tube with a Teflon-lined septum. The tube was evacuated and backfilled with argon (3 cycles). Solvent (1.0 mL), ethylene glycol (111 μL, 2.0 mmol; for entries 2, 4, 6, 8, 10), 5-iodo-m-xylene (144 μL, 1.0 mmol) and thiophenol (103 μL, 1.0 mmol) were added by syringes at room temperature. The tube was heated to 80° C. and stirred for 20 hours. The reaction mixture was then allowed to reach room temperature. Ethyl acetate (approx. 5 mL) and dodecane (227 μL, GC standard) were added. The aliquot was analyzed by GC or GC-MS. See FIG. 9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06888032B2 |
|---|
| Source dataset | uspto-grants-2005_05 |
|---|
| ORD ID | ord-643e7f62211d4e489fe9946b60d116c9 |
|---|
| Source note | uspto-grants-2005_05 |
|---|
