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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2180724Generated: October 31, 2026

(2-Hydroxyphenyl)acetic acid → 2-[(2-Hydroxyphenyl)acetamido]butyric acid isobutyl ester

https://huagongshe.com/reaction/2180724

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Hydroxyphenyl)acetic acidHCID 11970—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-Hydroxyphenyl)acetamido]butyric acid isobutyl esterHCID 53717695—

Reaction Steps

Following General Procedure I′ above and using 2-hydroxyphenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06888022B2
Source datasetuspto-grants-2005_05
ORD IDord-0724f283845a498b96639804b08f33e7
Source noteuspto-grants-2005_05