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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2180728Generated: October 30, 2026

o-Tolylacetic acid → 2-[(2-methylphenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/2180728

Reaction equation

Participants

RoleNameHCIDCharge
Reactanto-Tolylacetic acidHCID 69519—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-methylphenyl)acetamido]butyric Acid Iso-butyl EsterHCID 54573498—

Reaction Steps

Following General Procedure I′ above and using 2-methylphenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06888022B2
Source datasetuspto-grants-2005_05
ORD IDord-ff08c1ec455845e7a4b8364a29528b90
Source noteuspto-grants-2005_05