Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2180729Generated: October 30, 2026

Benzeneacetic acid, 2-fluoro- → 2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/2180729

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzeneacetic acid, 2-fluoro-HCID 67979—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl EsterHCID 53643249—

Reaction Steps

Following General Procedure I′ above and using 2-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06888022B2
Source datasetuspto-grants-2005_05
ORD IDord-11c58d7b1c2446f8bf30ed6367036cf4
Source noteuspto-grants-2005_05