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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2180733Generated: October 30, 2026

2-Thiopheneacetic acid → 2-[(2-Thienyl)acetamido]butyric acid isobutyl ester

https://huagongshe.com/reaction/2180733

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneacetic acidHCID 15970—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-Thienyl)acetamido]butyric acid isobutyl esterHCID 54443682—

Reaction Steps

Following General Procedure I′ above and using 2-thiopheneacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06888022B2
Source datasetuspto-grants-2005_05
ORD IDord-5571be18e93340738110340e9150438c
Source noteuspto-grants-2005_05