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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2180737Generated: October 30, 2026

3-(Methylthio)phenylacetic acid → N-[(3-methylthiophenyl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/2180737

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Methylthio)phenylacetic acidHCID 2737461—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3-methylthiophenyl)acetyl]alanine Iso-butyl EsterHCID 15481777—

Reaction Steps

Following General Procedure I′ above, and using 3-methylthiophenylacetic acid (CAS#18698-73-2) and alanine iso-butyl ester (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06888022B2
Source datasetuspto-grants-2005_05
ORD IDord-ae4d8e8377f248cf8bf1be720732ab9f
Source noteuspto-grants-2005_05