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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2180738Generated: October 31, 2026

2-(1-Benzofuran-2-yl)acetic acid → N-[(benzofuran-2-yl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/2180738

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1-Benzofuran-2-yl)acetic acidHCID 11105888—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(benzofuran-2-yl)acetyl]alanine Iso-butyl EsterHCID 15481779—

Reaction Steps

Following General Procedure I′ above, and using benzofuran-2-ylacetic acid (Maybridge) and alanine iso-butyl ester (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06888022B2
Source datasetuspto-grants-2005_05
ORD IDord-78f260c87f634872a7dda6ea34610b4c
Source noteuspto-grants-2005_05