Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2180742Generated: October 31, 2026

3-Thiophenacetic acid → N-[(3thienyl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/2180742

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Thiophenacetic acidHCID 23404—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3thienyl)acetyl]alanine Iso-butyl EsterHCID 53969374—

Reaction Steps

Following General Procedure I′ above, and using 3-thiopheneacetic acid (Aldrich) and alanine iso-butyl ester (prepared following General Procedure I′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06888022B2
Source datasetuspto-grants-2005_05
ORD IDord-db3665be3d53416ca0c9f19b683dc362
Source noteuspto-grants-2005_05